Other tumor cell lines, including anaplastic thyroid carcinoma (8505C), fibrosarcoma (HT-1080), hepatocellular carcinoma (SK-Hep-1, SNU-475, SNU-423, SNU-387, HepG2), gastric adenocarcinoma (MKN-45), head and neck cancer (A-253, Detroit 562, SCC-9, FaDu), melanoma (A375, SK-Mel-24, SK-Mel-28, C8161, UACC257), ovarian cancer (PEA-1, PEA-2), small cell lung cancer (NCI-H69, NCI-H446), and breast cancer (MCF-7, MDA-MB-231), also displayed intracellular BAG3 expression and BAG3 release, although secretion levels varied among different lines. The gene discussed is BAG3; the disease is head and neck cancer.