GPAA1 and colorectal carcinoma: Analysis of immune subtype-specific expression patterns indicated substantial elevation of GPAA1 in the C1 (wound healing) subtype (chi-square test, p < 0.05; Figure 2C), which is characterized by angiogenic gene signatures, enhanced proliferation, and Th2-skewed immune infiltration, and frequently observed in CRC and lung squamous cell carcinoma.