Studies show a close relationship between mutations in the STK11 tumor suppressor gene and various female reproductive tract cancers, as seen in Peutz-Jeghers syndrome (PJS), which manifests as various female reproductive tract tumors, such as endometrial carcinoma, cervical mucinous adenocarcinoma, and ovarian tubular sex cord tumors. This evidence concerns the gene STK11 and endometrial carcinoma.