Currently, only a subset of genes, including HNF1A, GCK, HNF4A, HNF1B, PDX1, NEUROD1, INS, ABCC8, and KCNJ11 are considered to have definitive or strong evidence supporting their causative role in MODY, while APPL1 has only limited evidence. Here, NEUROD1 is linked to MODY.