This notion aligns with the findings of Sung et al., where carcinosarcomas consistently demonstrated diminished or absent expression of epithelial markers (E-cadherin, claudin-3, and claudin-4), along with varying levels of expression of mesenchymal markers (S100A4, α-SMA, PDGFRα, and β-catenin). The gene discussed is CLDN3; the disease is carcinosarcoma.