Clinical trials with Lactobacillus rhamnosus JYLR-127 demonstrate significant improvements in post-surgical constipation, with defecation frequency increasing from 2.06 to 3.04 times/week and a concurrent reduction in inflammatory markers (CRP decreased from 24.45 to 15.42 mg/L) (Han et al., 2024). This evidence concerns the gene CRP and Constipation.