Therefore, the establishment of routine follow-up measures and ongoing monitoring is essential after splenectomy.[9] Several indicators have been studied and applied to evaluate the occurrence, progression, and prognosis of cance, including the Royal Marsden Hospital score (which combines albumin, lactate dehydrogenase [LDH], and metastatic burden) and the neutrophil-to-eosinophil ratio (NER).[23,24] They have been shown to have some reference value in determining the prognosis of cancer, especially for solid tumors like gastrointestinal tract tumors. The gene discussed is ALB; the disease is cancer.