A substantial body of evidence from numerous studies has confirmed that the proliferative capacity of T lymphocytes and the detection of inflammatory factors serve as effective indicators of the inflammatory state within the body.[8,9] Several biomarkers, including C-reactive protein (CRP), interleukin-6 (IL-6), interleukin-10 (IL-10), and NLR, have been identified as closely associated with the occurrence and prognosis of AF as well as adverse cardiovascular events.[10–12] Any cause of inflammatory response in the body may increase the risk of AF development. The gene discussed is CRP; the disease is atrial fibrillation.