The presence of the BCR::ABL1 fusion gene resulting from the translocation t(9;22)(q34;q11.2) is typically associated with the blast phase of CML.[10,11] Moreover, when the patient underwent a resection for a left frontoparietal hemangioma 3 years ago, the blood routine showed no abnormalities, and the patient had no history of CML nor exhibited splenomegaly. This evidence concerns the gene BCR and Splenomegaly.