The expression of miR-92a-3p, miR-423-5p, and miR-320a-3p in T lymphocytes of Kazakh hypertensive patients is downregulated, leading to increased expression of inflammatory factors such as IL-17 and IFN-γ, the elevation of IL-6, and the occurrence of hypertension. The gene discussed is IFNG; the disease is hypertensive disorder.