Since the role of lymphocytes in the development of hypertension was determined, researchers have been continuously exploring the functional role of lymphocytes in the pathogenesis of hypertension.[1] Usually, in the body, the aggregation and activation of lymphocytes caused by various diseases or exogenous stimuli damage or repair the body by promoting the release of corresponding cytokines.[2] The effector molecule of the renin angiotensin system, angiotensin II, induces hypertension. The gene discussed is AGT; the disease is Hypertension.