A strong effect of ADC treatment, with a pronounced delay in tumor growth and a markedly increased survival of the treated mice, was also observed in the patient-derived NCI-Meso79 model, which showed a more homogeneous expression of uPARAP on the tumor cells and a lower degree of fibroblast infiltration [Fig. 6A (left and middle)]. This evidence concerns the gene MRC2 and neoplasm.