Moreover, neither EHMT2 knockdown, EHMT2 knockout, nor treatment with UNC0642, A366, or BRD4770 affected cancer cell growth in a clonogenic assay, indicating that the impact of EHMT2 on tumor growth is largely NK cell-driven (cancer cell-extrinsic) (Appendix Fig. S8A–C). This evidence concerns the gene EHMT2 and cancer.