Since TGF-β1 can promote immune evasion by acting on both cancer cells and NK cells (Batlle and Massague, 2019), we asked if the conditioned media collected from EHMT2 inhibitor-treated cells or AZGP1- and TGF-β1-expressing cells could influence NK cell-mediated cytotoxicity. This evidence concerns the gene TGFB1 and cancer.