Regression was enhanced for CXCL10-secreting tumours, with three animals being tumour-free by day 22, then relapsing after day 26, as the CAR T cell BLI signal disappeared (median survival: 14 days, i.e. +27% compared with unmodified tumour-harbouring animals; Fig. 6d, Supplementary Figs. 20a, b, e, and Supplementary Note 14). This evidence concerns the gene CXCL10 and neoplasm.