Metabolic data showed that TeNT group mice exhibited a significant increase in body weight (p = 0.0004), accompanied by increased food intake (p = 0.0006), elevated gWAT and liver weight (p = 0.0050, p = 0.0232), an increase in both the size and number of lipid droplets in gWAT (p = 0.0010, p = 0.0366), in addition to impaired glucose tolerance and insulin sensitivity (p = 0.0070, p = 0.0111, p = 0.0165, p = 0.0007) (Fig. S3D–I). This evidence concerns the gene INS and Impaired glucose tolerance.