MKI67 and neoplasm: Consistent with results of reduced tumor size, PLX3397 + PL or PLX3397 + SAHA significantly reduced Ki-67+ cells (Fig. 6F, G), vimentin expression (Fig. 6H, I), but increased cleaved-caspase3+ cells (Fig. 6J, K) in G422TN-tumor compared to their corresponding monotherapy groups.