IL17A and parasitic infectious disease: A similarpattern has been reported in Plasmodium berghei malaria, where IL-33/ST2 deficiency did not affect parasitemia,but is crucial in regulating pathology., Importantly,the absence of parasitemia differences does not preclude altered parasiteburden in tissues, as described for IL-17 in Trypanosomabrucei infection. Notably,the accelerated mortality observed in ST2–/– mice points to immunopathological drivers rather than uncontrolledparasite replication.