The KEGG enrichment revealed that the main pathways activated are neurotrophin signaling pathway, apoptosis, proteoglycans in cancer, FoxO signaling pathway, ErbB pathway, etc. Differential expression analysis of the most prominent hub gene TP53 in the case of pancreatic cancer showed different pattern of expression as well as prognostic implications. The gene discussed is EGFR; the disease is pancreatic neoplasm.