While the exact molecular effects of overexpressed P53 on the cell cycle in pancreatic cancer are not fully elucidated, one of the identified pro-metastatic mechanisms of P53 in the same context is through stimulating the expression of PDGF receptor b, which mediates cell invasion, tumor angiogenesis and stoma development [9]. The gene discussed is TP53; the disease is familial pancreatic carcinoma.