Subtype analysis demonstrated that significantly difference between high and low SDC1 expressed in Breast invasive carcinoma (BRCA), GBM, head and neck squamous cell carcinoma (HNSC), KIRC, Lung adenocarcinoma (LUAD) and Lung squamous cell carcinoma (LUSC) (Fig. 1A–C). Here, SDC1 is linked to invasive breast carcinoma.