In tumor stemness analysis, we found that SDC1 was positively correlated with the scores for DNA, EREG-methss, DMPss, ENHss, RNAss and EREG in STES, THTM, but SDC1 expression was negatively correlated with the scores for DNA, EREG-methss, DMPss, ENHss, RNAss and EREG in TGCT, LUAD in TCGA dataset. The gene discussed is SDC1; the disease is neoplasm.