SDC1 and pheochromocytoma-paraganglioma: In this study, we used The Cancer Genome Atlas (TCGA) dataset indicating that SDC1 was significantly upregulated in a wide range of cancers compared with normal tissue but was downregulated in kidney renal clear cell carcinoma (KIRC), kidney chromophobe (KICH), Kidney papillary cell carcinoma (KIRP) and Pheochromocytoma and Paraganglioma (PCPG).