These observations suggest that OMs are molecularly distinct from other odontogenic neoplasms and may rely more on epigenetic dysregulation, as demonstrated by hypomethylation of tumor suppressor genes including CDKN1A, CDKN1B, CDKN2A, TP53, and RB1 [31, 32]. The gene discussed is CDKN1A; the disease is opsoclonus-myoclonus syndrome.