Women with low serum osteocalcin (Q1) had significantly poorer gait function (gait speed (p = 0.001; p for trend < 0.001), more steps taken (p = 0.003; p for trend 0.004)), higher inflammation (p < 0.001; p for trend < 0.001), and a larger proportion had diabetes (p for trend < 0.001) and polypharmacy (p for trend < 0.001), compared to those with highest osteocalcin levels (Q5). The gene discussed is BGLAP; the disease is diabetes mellitus.