To this end, CD3+ CD4+ T cells and CD19+ B cells infiltrating primary tumors (TILs) and draining LNs were sorted on days 11 and 21 after tumor implantation (Supplementary Fig. S5A and S5B) and cultured in vitro in the presence of 4T1 sAg (Fig. 7A). This evidence concerns the gene CD4 and neoplasm.