Notably, a previous study examining the sequences of DVGs produced during LCMV and Candid#1 infection also detected products of the S segment in which large parts of either the NP or GPC gene were deleted (24), some of which then closely resemble the S segment 2.1 kb DVG we identified for TCRV (Fig. 3), supporting that such DVGs are a common feature of infection with several different arenaviruses. This evidence concerns the gene GYPC and infection.