We confirmed increased expression of ISGs (IFI44L, IFIT1B, and OAS1) in a validation cohort of aSLE patients recruited in the UK using qPCR but were unable to validate increased NGPs (MMP8, MPO, LCN2, and LTF) in these patients (Supplementary Figure S3a) likely due to low n-numbers (n = 5–6) which were insufficient to capture the heterogeneity in ISG and NGP expression between interferon ‘high’ and interferon ‘low’ SLE patients. This evidence concerns the gene BANF1 and systemic lupus erythematosus.