According to Figure 2A,C, glioma tissues had a higher percentage of positive cells for RIP2, Iba1, IL‐1β, and CD206 than non‐tumor tissues (p < 0.05), and the high‐grade glioma group had higher expression of each signal than the low‐grade glioma group (p < 0.05). This evidence concerns the gene IL1B and central nervous system cancer.