In drug discovery, an antialcoholic fatty liver disease (AFLD) polysaccharide, APFC‐2, isolated and purified from Cornus officinalis (Asiatic dogwood), has been demonstrated to significantly ameliorate alcohol‐induced hepatic steatosis in both HepG2 cells and AFLD mouse livers by modulating the liver kinase B1 (LKB1)/AMPK signaling pathway [251]. The gene discussed is STK11; the disease is fatty liver disease.