ABCB1 and cancer: ,36 These transporters, which include P-gp/ATP binding cassette subfamily B member 1 (ABCB1), multi-drug resistance protein 2 (MRP2)/ATP-binding cassette subfamily C member 2 (ABCC2), and breast cancer resistance protein (BCRP)/ATP-binding cassette subfamily G member 2 (ABCG2), along with other members of the MRP/ABCC family, play a crucial role in removing anti-cancer drugs from cells.