In a study published in 2021, researchers show that the level of the lncRNA PTENP1-AS is promoted by the transcription factor CCAAT/enhancer binding protein beta (CEBPB) transcription factor in melanoma cell lines that are resistant to B-Raf proto-oncogene, serine/threonine kinase (BRAF) inhibitors.84 Here, BRAF is linked to melanoma.