F2 and blood coagulation disease: Similarly, procalcitonin (PCT) levels (median 3.0 [interquartile rage: 0.61, 22.16] μg/L), lactate levels (mean 3.3 ± 2.1 mmol/L), and markers of coagulopathy (prothrombin time [PT], international normalized ratio [INR], activated partial thromboplastin time [APTT], and D-dimer) and renal dysfunction (creatinine and urea) on admission were significantly more deranged in the persistent TP group than in the other two groups (all p < 0.001).