Additionally, unique copy number variations (CNVs) and single-nucleotide polymorphisms (SNPs), such as MTHFR (C677T, A1298C), VEGF (C2578A, G1154A, C634G), and MTRR (A66G, C524T), are associated with CHD [5,6]. The gene discussed is MTHFR; the disease is coronary artery disorder.