To date, Z‐DNA binding protein 1 (ZBP1)‐, Absent in Melanoma (AIM)‐, receptor‐interacting serine/threonine‐protein kinase 1 (RIPK1)‐, and NLR family pyrin domain containing 12 (NLRP12)‐ PANoptosomes have been characterized at the molecular level (Pandeya and Kanneganti 2024). Here, RIPK1 is linked to melanoma.