To determine whether autoimmune disease is associated with altered FDFT1 gene expression in immune cells, we performed a differential analysis of FDFT1 expression in immune cells from SLE patients, MS patients, RA patients, and healthy subjects using single-cell or bulk RNA-seq data (GSE138266 [66], E-GEAD-397 [67]). The gene discussed is FDFT1; the disease is systemic lupus erythematosus.