To test this, we isolated CD4 + T cells from human tonsil as a rich source of differentiated TFH and Th17 cells, stimulated them in the presence vs. absence of lapaquistat, and measured the secretion of TFH/Th17 cytokines known to support B cell antibody production and have important roles in the immunopathology characteristic of MS and SLE. Here, CD4 is linked to systemic lupus erythematosus.