In fibrotic diseases, KIF4A is a critical gene implicated in idiopathic pulmonary fibrosis (IPF), showing upregulation in pulmonary fibrosis models; the traditional Chinese medicine formula Jinshui Huanxian (JHF) can reverse its aberrant expression and improve fibrotic pathology, highlighting its potential as a therapeutic target in IPF [126]. The gene discussed is KIF4A; the disease is pulmonary fibrosis.