Strikingly, we could demonstrate that therapeutic inhibition of ERBB2 strongly induces MHC-I expression in different human and murine SCLC cell lines with and without IFNγ co-stimulation (Fig. 3k, l; Supplementary Fig. 5a–c) without affecting neuroendocrine differentiation (Supplementary Fig. 8). Here, IFNG is linked to small cell lung carcinoma.