NFKB1 and coronary artery disorder: We further characterized that HFD feeding increased hepatic NF-κB phosphorylation compared to CHD, which was normalized by choline supplementation, although this could also be a result of variable NF-κB protein levels between samples (Fig. 2i,j), a pattern that was also observed for expression of acute-phase proteins that are typically upregulated in response to tissue inflammation33 (Saa1, Saa2 and Saa3; Fig. 2k–m).