NEFL and Sepsis: NfL concentrations were significantly higher in patients with ME at day 3 (16.8 [12.9, 77.5] pg/ml vs. 10.7 [8.6, 12.2] pg/ml, p = 0.011) and day 5 (16.2 [6.8, 170.4] pg/ml vs. 12.0 [7.9, 14.3] pg/ml, p = 0.005) compared to patients with sepsis (Fig. 2).