In the intraperitoneal metastasis model, continuous bioluminescence imaging showed that mice inoculated with Il7r-KO cells had a reduced tumor burden compared with mice inoculated with Il7r-wide-type (Il7r-WT) cells (Fig. 1J, K), along with fewer peritoneal metastatic nodules (Fig. 1L and Supplementary Fig. S1E)—especially in common metastatic sites such as the peritoneum, intestinal tract, and diaphragm. Here, IL7R is linked to neoplasm.