ANGPT2 and acute respiratory distress syndrome: Univariate analysis further confirmed this association, showing that patients with Ang-2 levels ≥ 5896 pg/mL had 88% lower odds of progressing to RIARDS compared to those with Ang-2 levels < 5896 pg/mL (OR = 0.120, 95% CI: 0.044–0.325, p-value< 0.001), indicating that elevated Ang-2 is significantly associated with a lower likelihood of recovery from ARDS.