In sciatic nerves, CIS elevated NF-κB (+24%,p < 0.05), TNF-α (+21%,p < 0.001), IL-6 (+40%,p < 0.001), MDA (+35%), and TOS (+18%), while reducing TAS by 18% (p < 0.05), as shown inTable 4. Here, NFKB1 is linked to in situ carcinoma.