Analysis of the mRNA expression profile of VEGF-A revealed similar characteristics in terms of tumor depth and surface area: the mean RQ at the tumor depth for the whole group was 4.48 ± 4.99 versus 3.56 ± 3.20 at the tumor surface; the median RQ values were 2.54 and 2.47, respectively. This evidence concerns the gene VEGFA and neoplasm.