Multi‐component interventions which have included whole pathway approach [11, 14] specific guidelines [15], staff education [11, 14, 15], enhanced communication [11, 14, 15], early identification and optimisation [11, 14, 15], in‐reach diabetes specialist team input [11, 14, 15] and patient empowerment [11] have led to reduction in reported insulin errors [1, 15] and reductions in hypoglycaemia [11, 14, 15] and hyperglycaemic events [11]. This evidence concerns the gene INS and diabetes mellitus.