DNE-xQTL integration identified ten genes spanning 7 genomic loci associated with telomere length and/or AD that converge on ciliary function through two possible mechanisms: extracellular vesicle-mediated intercellular communication (BIN1, CBY1, DNAJC5, TRIM26, GGT7 via iAging3), and structural regulation of cilia and autophagy (MAP4, KIF9, SETD2, MON1A, USP19 via iAD1) (Figure 5g). This evidence concerns the gene USP19 and Alzheimer disease.