They were AD Developmental and epileptic encephalopathy (DEE) 11 (SCN2A c.877A>G, p.Thr293Ala, MIM:613721); DEE7 (KCNQ2 c.46G>A, p.Gly16Arg, MIM:613720); and DEE27 (GRIN2B c.2749T>C, p.Ser917Pro, MIM:616139). This evidence concerns the gene KCNQ2 and Alzheimer disease.