A more complicated example was infant 1253290 with LP genotypes for both CHD7-CHARGE syndrome (prevalence 8/100,000 births; infant mortality rate 20%) and NODAL-Heterotaxy 5 (prevalence 1/100,000 births; infant mortality rate 23%; SUID PRR 15.1; Fig. 3b). The gene discussed is NODAL; the disease is CHARGE syndrome.