In addition to the encephalopathies mentioned above, death certificate phenotypes narrowed the differential diagnosis in two cases: One had phenotypes R95 (SIDS) and congenital encephalopathy and WGS findings of ATP1A2-DEE98 (MIM: 619605)10–16,20,25–30; The other had phenotypes W75 (Accidental Suffocation and Strangulation in Bed) and abnormal chromosome morphology, and WGS identified Jacobsen syndrome (Chr 11q23.3-qter del; MIM: 147791). Here, ATP1A2 is linked to Jacobsen syndrome.