FGF2 and ulcer disease: Zheng et al. developed a multifunctional MN patchusing HA andhydroxypropyl trimethylammonium chloride chitosan (HACC) loaded withdexamethasone (DXMS) and basic fibroblast growth factor (bFGF) fororal ulcer healing. This structural designenabled the effective penetration of the oral mucosal tissue.