AKT1 and breast cancer: Earlier studies reported the anticancer activityof AGL against different types of human BC such as T-47D, BT549, MCF-7,and MDA-MB-231 cells by inhibition of cell cycle progression, affectingangiogenesis, generation of oxidative injury, or down-regulation ofstemness-related proteins.−,  Recent investigations demonstratedthat AGL triggers ROS-FOXM1, ER-α, and PI3K/AKT/mTOR signalingpathways to suppress cancer cell growth and malignancy., However, no study has been conducted so far for the effects of AGLon the SD rat-originated LA7 mammary tumor cell line.