To identify specific disease-related genes contributing to this enrichment, Venn diagram analysis was performed, revealing 34 RA-specific genes, 30 HCM-specific genes, and two shared genes—TGFB2 and TGFB3—both of which are known upstream regulators of inflammation and cardiac remodeling (Figure 5B). Here, TGFB3 is linked to rheumatoid arthritis.