EVs promote the proliferation, migration, and invasion of endometrial stromal cells (ESCs), inhibit ESCs apoptosis, and enhance the progression of endometriosis and angiogenesis by regulating the miR-761/histone deacetylase 1 (HDAC1) axis and activating the signal transduction and activator of transcription 3(STAT3)-mediated inflammation (Zhang et al., 2022). The gene discussed is HDAC1; the disease is endometriosis.