The results demonstrated that, compared to the IgG group, EPE significantly increased the mRNA transcription levels of IFN-γ, Granzyme B, Perforin, and CD107a, whereas NK1.1 cell depletion significantly abolished the EPE-induced elevation of these mRNA levels in tumor tissue cells (Figures 5J–M). The gene discussed is GZMB; the disease is neoplasm.