KAT6B mutations have been shown to predominantly correlate with GPS and SBBYSS, as well as other phenotypic spectra of neurodevelopmental syndromes, such as Noonan syndrome (OMIM #163950), and syndromic craniosynostosis [103, 153, 154, 155, 156, 157, 158]. Here, KAT6B is linked to Noonan syndrome.