Their proinflammatory functions are primarily mediated by IL‐17‐producing subsets—including Th17 cells, γδT17 cells, and group 3 innate lymphoid cells (ILC3s)—which promote osteitis and enthesopathy through the secretion of IL‐17, IL‐22, TNFα, and granulocyte–macrophage CSF (GM‐CSF) [127]. The gene discussed is IL17A; the disease is bone inflammation disease.