SPN and neoplasm: The immunohistochemistry results showed tumor cells CD3(+)、CD5(+)、CD43(+)、BCL2(Partial+)、BCL6(scattered weak+)、CD10 (–)、irregular proliferation of follicular dendritic cell (FDC) network defined by CD21/35 staining、CD20(-)、CD20(positive control+)、CD19(-)、CD22(-)、CD79a(-)、PCK(-)、P53 (scattered+, wild-type)、 CyclinD1(-)、IgD(-)、Ki-67 LI:50% in hot spot、plasma cells CD38(+)、CD138(+)、MUM1(+)、λ(+)>>κ(+, monoclonality)、EBER CISH(individual moderate cells+) (Figure 2).