SPN and neoplasm: The immunohistochemistry results showed tumor cells CD3(+)、CD5(+)、CD43(+)、LCA(+)、PD1(scattered weak+)、BCL6(scattered weak+)、CD4(scattered +)、C-MYC(+)、BCL2(+)、CD8 (–), plasma cells MUM(+)、λ(a little +)、κ(a little +), CD30 (approximately 5% moderate intensity+, positive control+)、GATA3 (slight+)、 P53 (scattered+, indicating wild-type)、 CD21 and CD23 (residual FDC network+)、CD35 (irregular proliferation of small focal FDC network+)、 CD20 (-, positive control+)、CD19(-)、PAX5(-)、CD10(-)、CyclinD1(-)、 PCK (-) Ki -67(LI about80%), EBER CISH (individual+, positive control+) (Figure 3).