GSTM1 and anemia: Admission evaluation included comprehensive imaging (Figure 2) and dermatological assessment, revealing high systemic tumor burden (SCC > 50 ng/mL; CA125 448.01 U/mL) and multi-organ dysfunction (1): severe anemia (Hb 71 g/L) accompanied by pancytopenia (lymphocytes 0.30×109/L) (2); chronic renal insufficiency (creatinine 114 μmol/L GFR ≈ 25 mL/min) (3); osteolytic metastasis at the L4 vertebra; and (4) scattered pulmonary inflammation.